Description

Benzonitrile, 4-(3R)-3-Piperidinyl- is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is of significant value for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals. The product is supplied with a CAS number of 1336679-42-5.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for creating new drug candidates.
• Organic Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds and piperidine-containing molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and scale-up of proprietary compounds.
• Academic Research: Utilized in university and institutional labs for methodological development in asymmetric synthesis.

Basic Information

Product Name	Benzonitrile, 4-(3R)-3-Piperidinyl-
CAS No.	1336679-42-5
Molecular Formula	C12H14N2
Molecular Weight	186.26 g/mol
Synonyms	4-[(3R)-3-Piperidinyl]benzonitrile; (R)-4-(Piperidin-3-yl)benzonitrile; (3R)-3-(4-Cyanophenyl)piperidine; 4-((R)-Piperidin-3-yl)benzonitrile; 4-(3R-Piperidinyl)benzonitrile; Benzonitrile, 4-[(3R)-3-piperidinyl]-; (R)-3-(4-Cyanophenyl)piperidine
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-(3R)-3-Piperidinyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.