Description

5-Bromo-3-Chloro-2-(2H-1,2,3-Triazol-2-yl)pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates halogen atoms and a triazole moiety, making it an essential precursor for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, drug discovery, and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, useful in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors, due to its electron-deficient aromatic system.
• Chemical Biology Probe: Utilized as a building block for developing molecular probes and tags to study biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	5-Bromo-3-Chloro-2-(2H-1,2,3-Triazol-2-yl)pyridine
CAS No.	1335057-78-7
Molecular Formula	C7H4BrClN4
Molecular Weight	259.49 g/mol
Synonyms	5-Bromo-3-chloro-2-(2H-1,2,3-triazol-2-yl)pyridine; 2-(5-Bromo-3-chloropyridin-2-yl)-2H-1,2,3-triazole; 2H-1,2,3-Triazole, 2-(5-bromo-3-chloro-2-pyridinyl)-; 1335057-78-7; 5-Bromo-3-chloro-2-(1H-1,2,3-triazol-2-yl)pyridine (tautomer form); BCPT; 2-(5-Bromo-3-chloro-pyridin-2-yl)-2H-[1,2,3]triazole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Chloro-2-(2H-1,2,3-Triazol-2-yl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.