Description

n-(tert-Butyl)-2,6-Dichloronicotinamide is a specialized nicotinamide derivative characterized by its tert-butyl substitution and dichloro functionalization on the pyridine ring. This compound serves as a crucial high-purity intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated nicotinamide structure.
• Chemical Research & Development: Serves as a versatile scaffold for heterocyclic chemistry and ligand synthesis in catalysis.
• Material Science Precursor: Potential intermediate for functional polymers or advanced organic materials requiring specific amide functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production.

Basic Information

Product Name	n-(tert-Butyl)-2,6-Dichloronicotinamide
CAS No.	1334612-24-6
Molecular Formula	C10H12Cl2N2O
Molecular Weight	247.12 g/mol
Synonyms	2,6-Dichloro-N-(tert-butyl)nicotinamide; N-tert-Butyl-2,6-dichloronicotinamide; 2,6-Dichloro-N-(1,1-dimethylethyl)-3-pyridinecarboxamide; tert-Butyl 2,6-dichloronicotinamide; 3-Pyridinecarboxamide, 2,6-dichloro-N-(1,1-dimethylethyl)-; N-(tert-Butyl)-2,6-dichloro-3-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-2,6-Dichloronicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.