Description

(R)-2-(Piperidin-3-Yl)Acetic Acid is a high-purity chiral building block of significant importance in modern pharmaceutical research and development. This compound serves as a key intermediate for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those targeting the central nervous system. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require enantiomerically pure intermediates to ensure the efficacy and safety of final drug products.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development of enantiomerically pure APIs.
• Asymmetric Synthesis: Serves as a versatile building block in asymmetric catalytic reactions and chiral pool synthesis.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship studies to optimize drug potency and selectivity.
• Process Chemistry & Scale-up: Used in the development and optimization of scalable, cost-effective synthetic routes for commercial manufacturing.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control.

Basic Information

Product Name	(R)-2-(Piperidin-3-Yl)Acetic Acid
CAS No.	1334509-89-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(R)-2-(3-Piperidyl)acetic acid; (3R)-2-Piperidineacetic acid; (R)-Piperidine-3-acetic acid; (R)-Homonipecotic acid; (R)-3-Carboxymethylpiperidine; (R)-BAY-1000393 intermediate; (R)-enantiomer of 2-(Piperidin-3-yl)acetic acid
EINECS	Contact for details

Quality Control

Our (R)-2-(Piperidin-3-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.