Description

(1S)-1-(Pyrazin-2-Yl)Ethan-1-Ol CAS NO 1334160-87-0 is a high-purity chiral alcohol derivative of pyrazine, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry and functional group make it an essential intermediate for constructing complex molecules with high enantiomeric purity. This compound is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Building block for developing advanced pesticides and herbicides with improved efficacy and selectivity.
• Ligand Synthesis: Precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Used in research laboratories for methodological studies in organic synthesis and stereochemistry.
• Material Science: Potential monomer or modifier for creating functional polymers with tailored properties.

Basic Information

Product Name	(1S)-1-(Pyrazin-2-Yl)Ethan-1-Ol
CAS No.	1334160-87-0
Molecular Formula	C6H8N2O
Molecular Weight	124.14 g/mol
Synonyms	(S)-1-(Pyrazin-2-yl)ethanol; (1S)-1-(2-Pyrazinyl)ethanol; (S)-(-)-1-(2-Pyrazinyl)ethanol; 2-(1-Hydroxyethyl)pyrazine (S-form); (S)-Pyrazin-2-yl-ethanol; (S)-2-(1-Hydroxyethyl)pyrazine; (1S)-1-Pyrazin-2-ylethan-1-ol; (S)-1-(2-Pyrazinyl)-1-ethanol
EINECS	Contact for details

Quality Control

Our (1S)-1-(Pyrazin-2-Yl)Ethan-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is subjected to comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, NMR, and GC/HPLC for purity and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.