Description

(L)-3,6-Bis(-Hydroxyethyl)-2,5-Diketopiperazine is a specialized chiral diketopiperazine derivative, a class of compounds known for their significant biological and chemical utility. This high-purity intermediate is valued for its role as a versatile building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in peptide-mimetic and constrained peptide drug discovery.
• Ligand and Catalyst Precursor: Used in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Science: Serves as a monomer or chain extender for creating novel biodegradable or functional polymers with specific stereochemistry.
• Cosmetic & Personal Care Actives: Potential application as a structural component in the synthesis of advanced skin-conditioning or anti-aging agents.
• Agrochemical Research: Employed as a building block for developing new chiral herbicides, fungicides, or plant growth regulators.
• Bioconjugation & Linker Chemistry: Utilized in the design of cleavable linkers or spacers for antibody-drug conjugates (ADCs) and other bioconjugates.

Basic Information

Product Name	(L)-3,6-Bis(-Hydroxyethyl)-2,5-Diketopiperazine
CAS No.	1333325-24-8
Molecular Formula	C8H14N2O4
Molecular Weight	202.21 g/mol
Synonyms	(L)-3,6-Bis(2-hydroxyethyl)-2,5-piperazinedione; (L)-3,6-Bis(2-hydroxyethyl)-2,5-diketopiperazine; (S)-3,6-Bis(2-hydroxyethyl)piperazine-2,5-dione; 2,5-Diketopiperazine-1,4-diethanol, (S)-; (S)-1,4-Bis(2-hydroxyethyl)-2,5-diketopiperazine; (S)-DKP-HE; L-BHEDKP; (S)-3,6-Di(2-hydroxyethyl)-2,5-dioxopiperazine
EINECS	Contact for details

Quality Control

Our (L)-3,6-Bis(-Hydroxyethyl)-2,5-Diketopiperazine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, chiral HPLC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.