Description

4-(Trifluoromethyl)Pyrimidine-2-Carbaldehyde is a high-value fluorinated pyrimidine building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides, leveraging the biological activity of the pyrimidine core.
• Material Science Research: Serves as a precursor for creating functionalized ligands and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	4-(Trifluoromethyl)Pyrimidine-2-Carbaldehyde
CAS No.	1333222-14-2
Molecular Formula	C6H3F3N2O
Molecular Weight	176.10 g/mol
Synonyms	2-Formyl-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-2-pyrimidinecarboxaldehyde; Pyrimidine-2-carbaldehyde, 4-(trifluoromethyl)-; 4-Trifluoromethylpyrimidine-2-carbaldehyde; 2-Pyrimidinecarboxaldehyde, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)-2-formylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Pyrimidine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.