Description

(S)-tert-Butyl 3-(Pyridine-3-Carbonylamino)Piperidine-1-Carboxylate CAS NO 1332765-68-0 is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with targeted biological activity. This advanced intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents.
• API Synthesis: Used in the construction of complex molecules for potential drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Employed in chiral pool synthesis to introduce the (S)-configured piperidine moiety into target compounds.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying enzyme and receptor function.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	(S)-tert-Butyl 3-(Pyridine-3-Carbonylamino)Piperidine-1-Carboxylate
CAS No.	1332765-68-0
Molecular Formula	C16H23N3O3
Molecular Weight	305.37 g/mol
Synonyms	1-Boc-3-[(pyridin-3-yl)carbonylamino]-(S)-piperidine; (S)-1-(tert-Butoxycarbonyl)-3-(nicotinamido)piperidine; (S)-tert-Butyl 3-(nicotinamido)piperidine-1-carboxylate; (S)-N-(1-Boc-piperidin-3-yl)nicotinamide; (S)-3-(Pyridine-3-carbonylamino)piperidine-1-carboxylic acid tert-butyl ester; (S)-Boc-3-(3-pyridylcarboxamido)piperidine; (S)-1-Boc-3-(3-pyridinecarboxamido)piperidine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-(Pyridine-3-Carbonylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.