Description

6-Bromo-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex heterocyclic molecules, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel therapeutic agents, particularly in the areas of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Oncology Drug Development: Employed in the creation of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Synthesis: Serves as a building block for compounds being investigated for neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological processes and identify new drug targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical R&D pipelines.

Basic Information

Product Name	6-Bromo-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester Hydrochloride
CAS No.	1332581-63-1
Molecular Formula	C10H8BrN2O2 • HCl
Molecular Weight	321.55 g/mol (Free base: 285.09)
Synonyms	6-Bromoimidazo[1,2-a]pyridine-8-carboxylic acid methyl ester hydrochloride; Methyl 6-bromoimidazo[1,2-a]pyridine-8-carboxylate hydrochloride; 6-Bromo-8-(methoxycarbonyl)imidazo[1,2-a]pyridine hydrochloride; 6-Bromoimidazo[1,2-a]pyridine-8-methyl carboxylate HCl; CAS 1332581-63-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-Imidazo[1,2-A]Pyridine-8-Carboxylic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.