Description

2-Pyridinecarboxylic Acid, 6-(Bromomethyl)-, 1,1-Dimethylethyl Ester CAS NO 1332367-16-4 is a high-value bromomethylated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its core value lies in the reactive bromomethyl group, which facilitates efficient functionalization and the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of complex drug molecules, especially in medicinal chemistry programs targeting neurological and oncological diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Material Science Research: Utilized as a monomer or functionalization agent in the development of novel polymers and advanced organic materials.
• Custom Synthesis and R&D: A fundamental starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 6-(Bromomethyl)-, 1,1-Dimethylethyl Ester
CAS No.	1332367-16-4
Molecular Formula	C12H16BrNO2
Molecular Weight	286.17 g/mol
Synonyms	tert-Butyl 6-(bromomethyl)picolinate; 6-(Bromomethyl)picolinic Acid tert-Butyl Ester; 2-Pyridinecarboxylic Acid, 6-(Bromomethyl)-, 1,1-Dimethylethyl Ester; Picolinic Acid, 6-(Bromomethyl)-, tert-Butyl Ester; tert-Butyl 6-(Bromomethyl)-2-pyridinecarboxylate; 6-Bromomethyl-picolinic Acid tert-Butyl Ester; (6-Bromomethyl-pyridin-2-yl)-carboxylic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarboxylic Acid, 6-(Bromomethyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.