Description

tert-Butyl 4-(4-Bromothiazol-2-Yl)-5,6-Dihydropyridine-1(2H)-Carboxylate is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular architecture, which serves as a critical intermediate for constructing complex pharmacologically active scaffolds. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and dihydropyridine motifs.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme function and biological pathways due to its ability to be further functionalized.
• Material Science Research: Serves as a building block for advanced organic materials, such as ligands for catalysts or components in organic electronic devices.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific bromo-thiazole intermediates.

Basic Information

Product Name	tert-Butyl 4-(4-Bromothiazol-2-Yl)-5,6-Dihydropyridine-1(2H)-Carboxylate
CAS No.	1332301-87-7
Molecular Formula	C13H17BrN2O2S
Molecular Weight	345.26 g/mol
Synonyms	1-BOC-4-(4-Bromo-2-thiazolyl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-4-(4-bromo-2-thiazolyl)-1-pyridinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(4-bromothiazol-2-yl)-1,2,3,6-tetrahydropyridine; tert-Butyl 4-(4-bromo-1,3-thiazol-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate; 4-(4-Bromothiazol-2-yl)-1-Boc-1,2,3,6-tetrahydropyridine; BOC-4-(4-Bromothiazol-2-yl)-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Bromothiazol-2-Yl)-5,6-Dihydropyridine-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.