Description

Aflatoxin M1-D3 is a stable isotope-labeled internal standard, specifically deuterated at three positions, which is essential for the accurate quantification of Aflatoxin M1 in complex matrices. This high-purity analytical standard is critical for ensuring data integrity and regulatory compliance in sensitive food safety and clinical diagnostic testing. It is primarily required by analytical laboratories, food safety monitoring agencies, and diagnostic manufacturers engaged in liquid chromatography-mass spectrometry (LC-MS/MS) method development and routine analysis.

Application

• Quantitative LC-MS/MS Analysis: Serves as an internal standard for the precise and accurate quantification of Aflatoxin M1 in milk, dairy products, and biological fluids.
• Food Safety Testing: Critical for regulatory compliance testing in dairy and infant formula to meet strict international maximum residue limits (MRLs).
• Method Development & Validation: Used to develop, optimize, and validate robust analytical methods in accordance with ISO, FDA, and EU guidelines.
• Clinical & Diagnostic Research: Enables reliable measurement of Aflatoxin M1 biomarkers in human and animal serum/urine for exposure assessment studies.
• Quality Control & Proficiency Testing: Employed by reference material producers and testing laboratories to ensure the accuracy of analytical results.
• Metabolism and Pharmacokinetic Studies: The deuterium label allows for the tracking and differentiation of the analyte from endogenous compounds in research.

Basic Information

Product Name	Aflatoxin M1-D3
CAS No.	1330042-13-1
Molecular Formula	C17H9D3O7
Molecular Weight	331.29 g/mol
Synonyms	4-Hydroxyaflatoxin B1-D3; [D3]-Aflatoxin M1; Aflatoxin M1 (trideuterated); AFM1-D3; 2,3,6a,9a-Tetrahydro-4-methoxy-1H,11H-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-d3; (6aR,9aR)-2,3,6a,9a-Tetrahydro-9a-hydroxy-4-methoxy-1H,11H-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-d3
EINECS	Contact for details

Quality Control

Our Aflatoxin M1-D3 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity for critical analytical applications. Each batch is fully characterized by NMR, HPLC, and high-resolution mass spectrometry to confirm identity, isotopic enrichment (>98 atom % D), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This compound is strictly light-sensitive and hygroscopic. For long-term storage, keep the primary container under an inert atmosphere in a desiccated freezer. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (HRMS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in acetonitrile, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.