Description

1-Methyl-5-(2,2,2-trifluoroethoxymethyl)pyrazol-3-amine is a specialized pyrazole derivative containing a trifluoroethoxy functional group, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine-containing moiety can impart desirable metabolic stability and bioavailability. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the trifluoroethoxy group for enhanced activity.
• Material Science Research: Used in the development of advanced organic materials and ligands for catalysis.
• Chemical Biology: Employed as a probe or scaffold in the study of biological targets and pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecule construction.

Basic Information

Product Name	1-Methyl-5-(2,2,2-trifluoroethoxymethyl)pyrazol-3-amine
CAS No.	1328640-31-8
Molecular Formula	C8H12F3N3O
Molecular Weight	223.20 g/mol
Synonyms	1-Methyl-5-((2,2,2-trifluoroethoxy)methyl)-1H-pyrazol-3-amine; 3-Amino-1-methyl-5-((2,2,2-trifluoroethoxy)methyl)-1H-pyrazole; 1-Methyl-5-(2,2,2-trifluoroethoxymethyl)-1H-pyrazol-3-amine; 1H-Pyrazol-3-amine, 1-methyl-5-((2,2,2-trifluoroethoxy)methyl)-; 1328640-31-8; 1-Methyl-5-(trifluoroethoxymethyl)pyrazol-3-amine
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-(2,2,2-trifluoroethoxymethyl)pyrazol-3-amine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.