Description

8-(4-Aminopiperidin-1-Yl)[1,2,4]Triazolo[4,3-A]Pyrazin-3(2H)-One is a high-purity heterocyclic organic compound of significant interest in advanced pharmaceutical research and development. This molecule serves as a critical synthetic intermediate or pharmacologically active scaffold, valued for its unique fused triazolopyrazine structure linked to an aminopiperidine moiety. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) drug development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for cancer and inflammatory disease therapies.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in vitro and in vivo to study enzyme function and validate novel drug targets.
• Preclinical Drug Development: Utilized in the synthesis of candidate compounds for pharmacological evaluation and toxicology studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery pipelines for global biotech and pharma clients.

Basic Information

Product Name	8-(4-Aminopiperidin-1-Yl)[1,2,4]Triazolo[4,3-A]Pyrazin-3(2H)-One
CAS No.	1325305-68-7
Molecular Formula	C12H16N6O
Molecular Weight	260.30 g/mol
Synonyms	8-(4-Aminopiperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyrazin-3(2H)-one; 8-(4-Aminopiperidin-1-yl)-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-3-one; 1325305-68-7; Aminopiperidinyl triazolopyrazinone; 1,2,4-Triazolo[4,3-a]pyrazin-3(2H)-one, 8-(4-amino-1-piperidinyl)-; 8-(4-Amino-1-piperidinyl)-1,2,4-triazolo[4,3-a]pyrazin-3(2H)-one
EINECS	Contact for details

Quality Control

Our 8-(4-Aminopiperidin-1-Yl)[1,2,4]Triazolo[4,3-A]Pyrazin-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.