Description

8-Chloro-1-Iodo-3-Isopropylimidazo[1,5-A]Pyrazine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its unique halogenated structure, featuring both chloro and iodo substituents, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging its halogenated imidazopyrazine core.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying biological pathways and target engagement.
• Material Science: Acts as a building block for advanced organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The iodo and chloro groups are excellent handles for versatile metal-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	8-Chloro-1-Iodo-3-Isopropylimidazo[1,5-A]Pyrazine
CAS No.	1320266-92-9
Molecular Formula	C9H9ClIN3
Molecular Weight	321.55 g/mol
Synonyms	8-Chloro-1-iodo-3-(propan-2-yl)imidazo[1,5-a]pyrazine; 3-Isopropyl-8-chloro-1-iodoimidazo[1,5-a]pyrazine; 1-Iodo-8-chloro-3-isopropylimidazo[1,5-a]pyrazine; Imidazo[1,5-a]pyrazine, 8-chloro-1-iodo-3-(1-methylethyl)-; 1320266-92-9; 8-Chloro-1-iodo-3-isopropyl-imidazo[1,5-a]pyrazine
EINECS	Contact for details

Quality Control

Our 8-Chloro-1-Iodo-3-Isopropylimidazo[1,5-A]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.