Description

(R)-4-[(R)-1-[7-(3,4,5-Trimethoxy-Phenyl)-[1,6]Naphthyridin-5-Yloxy]-Ethyl]-Pyrrolidin-2-One is a high-purity chiral intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel therapeutic agents. It is primarily targeted at research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly in areas requiring sophisticated chiral synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Asymmetric Synthesis: Used in the development of stereoselective synthetic routes for complex organic molecules.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in analytical laboratories.
• Process Chemistry Development: Utilized in scaling up synthetic pathways from laboratory to pilot plant scale.
• Academic Research: Used in university and institutional labs for studies in organic chemistry, catalysis, and pharmacology.

Basic Information

Product Name	(R)-4-[(R)-1-[7-(3,4,5-Trimethoxy-Phenyl)-[1,6]Naphthyridin-5-Yloxy]-Ethyl]-Pyrrolidin-2-One
CAS No.	1319738-39-0
Molecular Formula	C25H28N2O5
Molecular Weight	436.50 g/mol
Synonyms	(R)-4-[(R)-1-[7-(3,4,5-Trimethoxyphenyl)-[1,6]naphthyridin-5-yloxy]ethyl]pyrrolidin-2-one; (R,R)-4-(1-((7-(3,4,5-Trimethoxyphenyl)-1,6-naphthyridin-5-yl)oxy)ethyl)pyrrolidin-2-one; UNII-0J8K9Q6V4F; 0J8K9Q6V4F; CHEMBL3186660; BDBM50389379; AKOS025147065; A1-008/31563066
EINECS	Contact for details

Quality Control

Our (R)-4-[(R)-1-[7-(3,4,5-Trimethoxy-Phenyl)-[1,6]Naphthyridin-5-Yloxy]-Ethyl]-Pyrrolidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including chiral purity verification by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.