Description

[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine, 5-(Trifluoromethyl)- is a high-value heterocyclic building block featuring a fused triazolopyridine core with a strategically positioned trifluoromethyl group. This compound is essential for medicinal chemistry and agrochemical research, where it serves as a key intermediate for introducing specific pharmacophores and modulating the physicochemical properties of target molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Precursor: Serves as a specialized ligand or monomer for creating functional polymers and advanced organic electronic materials.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, fluorinated nitrogen heterocycles.

Basic Information

Product Name	[1,2,4]Triazolo[1,5-A]Pyridin-2-Amine, 5-(Trifluoromethyl)-
CAS No.	1319067-64-5
Molecular Formula	C7H5F3N4
Molecular Weight	202.14 g/mol
Synonyms	5-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 5-(Trifluoromethyl)-1,2,4-triazolo[1,5-a]pyridin-2-amine; 2-Amino-5-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridine; 1319067-64-5; 5-Trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine; 5-CF3-[1,2,4]triazolo[1,5-a]pyridin-2-amine
EINECS	Contact for details

Quality Control

Our production of [1,2,4]Triazolo[1,5-A]Pyridin-2-Amine, 5-(Trifluoromethyl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is fully characterized and analyzed using advanced techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.