Description

6-Aminopyrazin-2-Yl-2-Boronic Acid is a specialized boronic acid derivative that serves as a crucial building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling it to act as a versatile intermediate in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex heterocyclic scaffolds for active ingredient development. Its application extends to materials science for the creation of novel organic electronic components.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic acid reagent for forming carbon-carbon bonds to construct complex biaryl and heteroaryl structures.
• Materials Science Research: Employed in the synthesis of organic semiconductors, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects requiring specific pyrazine-based architectures.

Basic Information

Product Name	6-Aminopyrazin-2-Yl-2-Boronic Acid
CAS No.	1315351-77-9
Molecular Formula	C4H6BN3O2
Molecular Weight	138.92 g/mol
Synonyms	6-Aminopyrazin-2-ylboronic Acid; (6-Aminopyrazin-2-yl)boronic Acid; 2-Amino-6-boronopyrazine; 6-Amino-2-pyrazinylboronic Acid; 6-Aminopyrazine-2-boronic Acid; B-(6-Amino-2-pyrazinyl)boronic Acid; 2-Pyrazinamine, 6-borono-; CAS 1315351-77-9
EINECS	Contact for details

Quality Control

Every batch of 6-Aminopyrazin-2-Yl-2-Boronic Acid undergoes rigorous analytical testing to ensure high purity and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and cGMP manufacturing environments. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and other relevant spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.