Description

6-(Tetrahydro-Furan-3-Yloxy)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, protected boronic acid ester building block crucial for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the precise and efficient construction of complex heterocyclic molecules, which are foundational to advanced material and pharmaceutical research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between pyridine derivatives and aryl/heteroaryl halides, enabling the synthesis of complex biaryl structures.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fused pyridine and tetrahydrofuran motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and advanced polymers where precise molecular control is required.
• Chemical Biology & Medicinal Chemistry: Facilitates the synthesis of tool compounds and probe molecules for target identification and validation in drug discovery programs.
• Process Chemistry & Scale-up: Provides a stable, handleable form of the boronic acid for optimization and kilogram-scale production of target molecules.

Basic Information

Product Name	6-(Tetrahydro-Furan-3-Yloxy)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1315351-11-1
Molecular Formula	C15H22BNO4
Molecular Weight	291.15 g/mol
Synonyms	6-[(Tetrahydrofuran-3-yl)oxy]pyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(tetrahydrofuran-3-yloxy)pyridine; 6-(Tetrahydrofuran-3-yloxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-(3-Tetrahydrofuranyloxy)-2-pyridineboronic acid pinacol ester; Pinacol 6-(tetrahydrofuran-3-yloxy)pyridine-2-boronate; CAS 1315351-11-1
EINECS	Contact for details

Quality Control

Our production of 6-(Tetrahydro-Furan-3-Yloxy)Pyridine-2-Boronic Acid Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials undergo comprehensive analytical characterization, including NMR (1H, 13C, 11B), HPLC, and GC analysis. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.