Description

4-(6-Aminopyridin-3-Yl)-N,n-Dimethylbenzamide CAS NO 1314987-53-5 is a high-purity, advanced pharmaceutical intermediate featuring a unique bifunctional aromatic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of targeted small molecule therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Kinase Inhibitor Development: The aminopyridine moiety makes it a valuable precursor for developing selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the creation of molecular probes to study biological processes and identify new therapeutic targets.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the cGMP production of clinical trial materials and commercial APIs.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	4-(6-Aminopyridin-3-Yl)-N,n-Dimethylbenzamide
CAS No.	1314987-53-5
Molecular Formula	C14H15N3O
Molecular Weight	241.29 g/mol
Synonyms	4-(6-Aminopyridin-3-yl)-N,N-dimethylbenzamide; N,N-Dimethyl-4-(6-aminopyridin-3-yl)benzamide; 4-(6-Amino-3-pyridinyl)-N,N-dimethylbenzamide; Benzamide, 4-(6-amino-3-pyridinyl)-N,N-dimethyl-; 1314987-53-5; 4-(6-Aminopyridin-3-Yl)-N,n-Dimethylbenzamide
EINECS	Contact for details

Quality Control

Our 4-(6-Aminopyridin-3-Yl)-N,n-Dimethylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.