Description

1,2,2-Trifluoropiperazin is a specialized fluorinated piperazine derivative, a high-value building block in advanced organic synthesis. Its unique structure, featuring three fluorine atoms, is critical for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the design and synthesis of next-generation herbicides and pesticides, where fluorine incorporation enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel fluorinated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and specialty materials with unique surface properties and chemical resistance.
• Fluorine Chemistry Research: An important reagent for academic and industrial research focused on exploring new C-F bond formation reactions and fluorine-specific transformations.

Basic Information

Product Name	1,2,2-Trifluoropiperazin
CAS No.	1314931-12-8
Molecular Formula	C4H7F3N2
Molecular Weight	140.11 g/mol
Synonyms	1,2,2-Trifluoro-piperazine; 1,2,2-Trifluoropiperazine; Piperazine, 1,2,2-trifluoro-; 2,2,3-Trifluoropiperazine; 1,2,2-Trifluoro-1,4-diazacyclohexane
EINECS	Contact for details

Quality Control

Our 1,2,2-Trifluoropiperazin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.