Description

3,5-Difluoro-4-Methylpyridin-2-Amine is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the amine group, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluoromethylpyridine moiety contributes to biological activity.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis and for creating novel organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring specific fluorinated pyridine architectures.

Basic Information

Product Name	3,5-Difluoro-4-Methylpyridin-2-Amine
CAS No.	1314514-97-0
Molecular Formula	C6H6F2N2
Molecular Weight	144.12 g/mol
Synonyms	2-Amino-3,5-difluoro-4-methylpyridine; 4-Methyl-3,5-difluoropyridin-2-amine; 3,5-Difluoro-4-methyl-2-pyridinamine; 4-Methyl-3,5-difluoro-2-aminopyridine; 2-Pyridinamine, 3,5-difluoro-4-methyl-; 1314514-97-0; 3,5-Difluoro-4-methylpyridin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-4-Methylpyridin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorinating agents. The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.