Description

tert-Butyl 3-(Hydroxymethyl)-5,6-Dihydroimidazo[1,2-A]Pyrazine-7(8H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic molecules, particularly those targeting central nervous system and oncological pathways. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially within the imidazopyrazine chemical class.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Serves as a key building block in the construction of complex molecules intended for preclinical and clinical development.
• Bioconjugation & Probe Development: The hydroxymethyl group provides a handle for further chemical modification, useful in creating labeled compounds for biochemical assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of pharmaceutical intermediates.

Basic Information

Product Name	tert-Butyl 3-(Hydroxymethyl)-5,6-Dihydroimidazo[1,2-A]Pyrazine-7(8H)-Carboxylate
CAS No.	1314391-41-7
Molecular Formula	C₁₂H₁₉N₃O₃
Molecular Weight	253.30 g/mol
Synonyms	tert-Butyl 3-(hydroxymethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-7-carboxylate; 7-Boc-3-(hydroxymethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine; 3-(Hydroxymethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 3-(hydroxymethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate; 7-Boc-3-hydroxymethyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine; tert-Butyl 3-(hydroxymethyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate; Boc-protected imidazopyrazine intermediate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Hydroxymethyl)-5,6-Dihydroimidazo[1,2-A]Pyrazine-7(8H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.