Description

1-(2-Fluorobenzyl)-3-Iodo-1H-Pyrazolo[3,4-B]Pyridine is a high-value, heterocyclic organic compound featuring a pyrazolopyridine core functionalized with iodine and a 2-fluorobenzyl group. This specific molecular architecture makes it a critical building block for pharmaceutical research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for lead optimization and scale-up.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated heterocyclic structure.
• Chemical Biology Probe Development: Employed in creating molecular probes for studying enzyme function and biological pathways due to its modifiable iodine handle.
• Material Science: Potential building block for organic electronic materials and metal-organic frameworks (MOFs) where its aromatic system and halogen atom are advantageous.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create more complex molecular architectures.

Basic Information

Product Name	1-(2-Fluorobenzyl)-3-Iodo-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1313738-72-5
Molecular Formula	C₁₃H₉FIN₃
Molecular Weight	353.14 g/mol
Synonyms	3-Iodo-1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 1-[(2-fluorophenyl)methyl]-3-iodo-; 1-(2-Fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine; 1313738-72-5; 3-Iodo-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine; 1-(2-Fluorobenzyl)-3-iodopyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)-3-Iodo-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.