Description

Methyl-(3-Piperazin-1-Yl-Propyl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical agents, particularly in medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its versatile piperazine scaffold.
• Peptidomimetic Synthesis: Serves as a backbone or side-chain component in the design of peptide-like molecules with enhanced metabolic stability.
• Ligand and Receptor Probe Development: Employed in creating chemical tools for biological target identification and validation.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	Methyl-(3-Piperazin-1-Yl-Propyl)-Carbamic Acid tert-Butyl Ester
CAS No.	1313712-68-3
Molecular Formula	C13H27N3O2
Molecular Weight	257.37 g/mol
Synonyms	tert-Butyl methyl(3-(piperazin-1-yl)propyl)carbamate; N-Boc-N'-methyl-3-(piperazin-1-yl)propylamine; 1-[3-[[(1,1-Dimethylethoxy)carbonyl](methyl)amino]propyl]piperazine; Methyl(3-piperazin-1-ylpropyl)carbamic acid 1,1-dimethylethyl ester; Boc-N-methyl-3-(piperazin-1-yl)propylamine; (3-(Piperazin-1-yl)propyl)(methyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Methyl-(3-Piperazin-1-Yl-Propyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.