Description

1-(4-Benzyl-Piperazin-1-Yl)-3-Hydroxy-2-Phenyl-Propan-1-One is a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a versatile building block in the development of complex pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic targets.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in route scouting and scale-up studies for the efficient manufacturing of target compounds.
• Custom Synthesis Building Block: Employed by fine chemical suppliers for the preparation of specialized libraries and custom molecules for client projects.
• Biochemical Tool Compound: Potential use in developing biochemical probes for studying specific enzyme or receptor interactions.

Basic Information

Product Name	1-(4-Benzyl-Piperazin-1-Yl)-3-Hydroxy-2-Phenyl-Propan-1-One
CAS No.	1313712-45-6
Molecular Formula	C20H24N2O2
Molecular Weight	324.42 g/mol
Synonyms	1-(4-Benzylpiperazin-1-yl)-3-hydroxy-2-phenylpropan-1-one; 3-Hydroxy-1-(4-benzyl-1-piperazinyl)-2-phenyl-1-propanone; 2-Phenyl-3-hydroxy-1-(4-benzylpiperazin-1-yl)propan-1-one; 1-(4-Benzylpiperazin-1-yl)-3-hydroxy-2-phenyl-1-propanone; 1313712-45-6; 1-Propanone, 1-(4-benzyl-1-piperazinyl)-3-hydroxy-2-phenyl-
EINECS	Contact for details

Quality Control

Our 1-(4-Benzyl-Piperazin-1-Yl)-3-Hydroxy-2-Phenyl-Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.