Description

tert-Butyl (3S,5R)-3-Amino-5-Methylpiperidine-1-Carboxylate is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into the backbone of peptide mimics and other bioactive compounds to modulate stability and receptor interaction.
• Chemical Biology Probe Development: Utilized in constructing molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	tert-Butyl (3S,5R)-3-Amino-5-Methylpiperidine-1-Carboxylate
CAS No.	1312810-39-1
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-3-amino-5-methylpiperidine (3S,5R)-; (3S,5R)-1-(tert-Butoxycarbonyl)-3-amino-5-methylpiperidine; tert-Butyl (3S,5R)-3-amino-5-methyl-1-piperidinecarboxylate; (3S,5R)-3-Amino-5-methylpiperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-(3S,5R)-3-Amino-5-methylpiperidine; Boc-(3S,5R)-Amp; (3S,5R)-3-Amino-5-methylpiperidine hydrochloride Boc-protected; (3S,5R)-5-Methylpiperidin-3-amine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (3S,5R)-3-Amino-5-Methylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.