Description

tert-Butyl (6-Chloro-5-Fluoro-4-Iodopyridin-3-Yl)Carbamate (Wxg00223) is a high-purity, multi-halogenated pyridine derivative designed for advanced pharmaceutical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its halogenated pyridine core for bioactivity.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to build complex molecular frameworks.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry and biochemical research due to its distinct halogen pattern.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Item	Details
Product Name	tert-Butyl (6-Chloro-5-Fluoro-4-Iodopyridin-3-Yl)Carbamate (Wxg00223)
CAS No.	1312755-61-5
Molecular Formula	C10H11ClFINO2
Molecular Weight	357.56 g/mol
Synonyms	Boc-6-Chloro-5-Fluoro-4-Iodo-3-Aminopyridine; tert-Butyl N-(6-Chloro-5-fluoro-4-iodopyridin-3-yl)carbamate; 3-((tert-Butoxycarbonyl)amino)-6-chloro-5-fluoro-4-iodopyridine; Boc-3-Amino-6-chloro-5-fluoro-4-iodopyridine; Wxg00223; 6-Chloro-5-fluoro-4-iodopyridin-3-amine, N-Boc protected; N-Boc-3-Amino-6-chloro-5-fluoro-4-iodopyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-Chloro-5-Fluoro-4-Iodopyridin-3-Yl)Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.