Description

tert-Butyl (2,6-Dichloro-5-Fluoropyridin-3-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic areas. It is primarily sought after by research institutions and manufacturers in the global pharmaceutical and agrochemical industries for the development of novel compounds. Its defined structure and purity are essential for ensuring the efficacy and consistency of the final drug products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• API Manufacturing: Integrated into multi-step synthesis routes for the production of target active pharmaceutical ingredients under GMP conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects.

Basic Information

Product Name	tert-Butyl (2,6-Dichloro-5-Fluoropyridin-3-Yl)Carbamate
CAS No.	1312755-60-4
Molecular Formula	C10H11Cl2FN2O2
Molecular Weight	281.11 g/mol
Synonyms	Boc-2,6-Dichloro-5-fluoro-3-aminopyridine; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,6-dichloro-5-fluoropyridine; tert-Butyl N-(2,6-dichloro-5-fluoropyridin-3-yl)carbamate; 2,6-Dichloro-5-fluoro-3-((tert-butoxycarbonyl)amino)pyridine; 2,6-Dichloro-5-fluoropyridin-3-yl-carbamic acid tert-butyl ester; (2,6-Dichloro-5-fluoropyridin-3-yl)carbamic acid tert-butyl ester; tert-Butyl (2,6-dichloro-5-fluoropyridin-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (2,6-Dichloro-5-Fluoropyridin-3-Yl)Carbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material for pre-clinical and clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.