Description

2-Bromo-5-Chloro-3-Fluoro-1-Methylpyridin-4(1H)-One is a high-value, multi-halogenated pyridinone derivative serving as a critical building block in advanced organic synthesis. Its unique halogen pattern makes it an indispensable intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel agrochemicals, pharmaceuticals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for synthesizing functionalized ligands, organic electronic materials, and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-5-Chloro-3-Fluoro-1-Methylpyridin-4(1H)-One
CAS No.	1312440-88-2
Molecular Formula	C6H4BrClFNO
Molecular Weight	240.46 g/mol
Synonyms	4(1H)-Pyridinone, 2-bromo-5-chloro-3-fluoro-1-methyl-; 2-Bromo-5-chloro-3-fluoro-1-methyl-4(1H)-pyridinone; 1-Methyl-2-bromo-5-chloro-3-fluoro-4-pyridone; 2-Bromo-5-chloro-3-fluoro-1-methylpyridin-4-one; 2-Bromo-5-chloro-3-fluoro-N-methyl-4-pyridone
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Chloro-3-Fluoro-1-Methylpyridin-4(1H)-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound should be considered moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.