Description

(S)-3-n-Cbz-Aminomethylmorpholine CAS NO 1312161-63-9 is a high-purity chiral morpholine derivative, specifically functionalized with a carboxybenzyl (Cbz) protecting group on the amine. This compound is a critical building block and intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• Peptidomimetic Research: Used to introduce constrained morpholine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a chiral auxiliary or ligand precursor in catalytic asymmetric transformations.
• Agrochemical Development: An intermediate in the research and production of advanced, targeted crop protection agents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific complex molecules under cGMP or research-grade conditions.

Basic Information

Product Name	(S)-3-n-Cbz-Aminomethylmorpholine
CAS No.	1312161-63-9
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	(S)-3-((((Benzyloxy)carbonyl)amino)methyl)morpholine; (S)-N-((Morpholin-3-yl)methyl)carbamic acid benzyl ester; (S)-Cbz-Aminomethylmorpholine; (S)-3-(Cbz-Aminomethyl)morpholine; (S)-3-(N-Carbobenzoxyaminomethyl)morpholine; Benzyl (S)-((morpholin-3-yl)methyl)carbamate; (3S)-3-[[(Benzyloxy)carbonylamino]methyl]morpholine
EINECS	Contact for details

Quality Control

Our (S)-3-n-Cbz-Aminomethylmorpholine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess, meeting the stringent requirements of research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.