Description

6-(Dimethylamino)Pyrazine-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. This compound matters because it provides a protected boronic acid functionality that is crucial for constructing complex heterocyclic scaffolds with precision and efficiency. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between pyrazine derivatives and aryl/heteroaryl halides, enabling the synthesis of complex biaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers, due to the electron-donating dimethylamino group.
• Ligand and Catalyst Development: Useful for synthesizing novel bidentate or tridentate ligands for metal catalysis.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	6-(Dimethylamino)Pyrazine-2-Boronic Acid Pinacol Ester
CAS No.	1311412-96-0
Molecular Formula	C12H20BN3O2
Molecular Weight	249.12 g/mol
Synonyms	6-(Dimethylamino)-2-pyrazineboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(dimethylamino)pyrazine; (6-(Dimethylamino)pyrazin-2-yl)boronic acid pinacol ester; 6-Dimethylaminopyrazine-2-boronic acid pinacol ester; 6-(N,N-Dimethylamino)pyrazine-2-boronic acid pinacol ester; 2-Borono-6-dimethylaminopyrazine pinacol ester; B-[6-(Dimethylamino)-2-pyrazinyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-(Dimethylamino)Pyrazine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.