Description

(E)-3-[4-(6-Dimethylamino-4-Trifluoromethyl-Pyridin-2-Yl)-Phenyl]-Acrylic Acid is a high-value, advanced pharmaceutical intermediate featuring a unique molecular architecture that combines a trifluoromethylpyridine core with an acrylic acid moiety. This compound is critical for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, agrochemicals, and specialty organic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, especially in oncology and central nervous system (CNS) research.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the biological activity of the trifluoromethylpyridine group.
• Organic Synthesis: Serves as a versatile precursor for creating complex organic molecules via reactions involving its acrylic acid functional group.
• Material Science: Potential monomer or additive in the research of specialty polymers with specific optical or electronic properties.
• Chemical Biology: Employed as a probe or linker molecule in bioconjugation and proteomics research due to its reactive double bond.

Basic Information

Product Name	(E)-3-[4-(6-Dimethylamino-4-Trifluoromethyl-Pyridin-2-Yl)-Phenyl]-Acrylic Acid
CAS No.	1311283-88-1
Molecular Formula	C17H15F3N2O2
Molecular Weight	336.31 g/mol
Synonyms	(E)-3-[4-(6-(Dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)phenyl]acrylic acid; 2-Propenoic acid, 3-[4-[6-(dimethylamino)-4-(trifluoromethyl)-2-pyridinyl]phenyl]-, (2E)-; (E)-3-(4-(6-(Dimethylamino)-4-(trifluoromethyl)pyridin-2-yl)phenyl)acrylic acid; 1311283-88-1; 4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-cinnamic acid (E-isomer)
EINECS	Contact for details

Quality Control

Our production of (E)-3-[4-(6-Dimethylamino-4-Trifluoromethyl-Pyridin-2-Yl)-Phenyl]-Acrylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.