Description

4-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Ylmethyl)-Piperazine-1-Carboxylic Acid (4-Chloro-Phenyl) Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in modern medicinal chemistry, enabling the development of targeted therapeutics. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for its precise molecular architecture.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the trifluoromethyl and chloropyridine motifs for enhanced bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring new structure-activity relationships (SAR).
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and fluorine-containing compounds.

Basic Information

Product Name	4-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Ylmethyl)-Piperazine-1-Carboxylic Acid (4-Chloro-Phenyl) Ester
CAS No.	1311279-57-8
Molecular Formula	C19H16Cl2F3N3O2
Molecular Weight	446.25 g/mol
Synonyms	4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methylpiperazine-1-carboxylic acid 4-chlorophenyl ester; 4-Chlorophenyl 4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-1-piperazinecarboxylate; 1-Piperazinecarboxylic acid, 4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-, 4-chlorophenyl ester; CAS 1311279-57-8
EINECS	Contact for details

Quality Control

Our production of 4-(3-Chloro-5-Trifluoromethyl-Pyridin-2-Ylmethyl)-Piperazine-1-Carboxylic Acid (4-Chloro-Phenyl) Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.