Description

n-Boc-2-Cyanothiomorpholine is a high-purity, protected thiomorpholine derivative, serving as a critical building block in modern organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex nitrogen- and sulfur-containing heterocycles, which are prevalent in active pharmaceutical ingredients. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides that incorporate thiomorpholine motifs for enhanced bioactivity.
• Peptidomimetics Research: Serves as a constrained, non-natural amino acid analog for creating stable peptide-like structures in medicinal chemistry.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Chemical Biology Probes: Utilized to create labeled compounds and activity-based probes for studying enzyme function and biological pathways.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique electronic or mechanical properties.

Basic Information

Product Name	n-Boc-2-Cyanothiomorpholine
CAS No.	1311254-50-8
Molecular Formula	C10H16N2O2S
Molecular Weight	228.31 g/mol
Synonyms	tert-Butyl 2-cyano-1,4-thiazepane-1-carboxylate; 1,1-Dimethylethyl 2-cyano-1,4-thiazepane-1-carboxylate; 2-Cyanothiomorpholine-1-carboxylic acid tert-butyl ester; Boc-2-cyanothiomorpholine; N-Boc-2-cyanothiomorpholine; 1-Boc-2-cyanothiomorpholine; tert-Butyl 2-cyano-1,4-thiazepan-1-carboxylate
EINECS	Contact for details

Quality Control

Our n-Boc-2-Cyanothiomorpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.