Description

Butanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3,3-Dimethyl- is a high-purity, protected amino acid derivative, specifically a Boc-protected 3,3-dimethylbutanoic acid analog. This compound is a critical building block in modern organic synthesis, offering a versatile handle for the controlled introduction of sterically hindered amino acid motifs. It is primarily needed by research and development laboratories, pharmaceutical intermediates manufacturers, and fine chemical producers engaged in the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to construct complex peptide sequences.
• Protease Inhibitor Research: Serves as a core scaffold or precursor in the development of enzyme inhibitors, particularly targeting proteases.
• Bioconjugation & Linker Chemistry: Employed to create custom linkers or to functionalize molecules for bioconjugation applications in drug delivery and diagnostics.
• Agrochemical Synthesis: Intermediate in the production of specialized agrochemicals requiring specific steric and functional properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	Butanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3,3-Dimethyl-
CAS No.	1310680-18-2
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	4-[(tert-Butoxycarbonyl)amino]-3,3-dimethylbutanoic acid; Boc-3,3-dimethyl-γ-aminobutyric acid; Boc-Dmgaba-OH; (4-{[(tert-Butoxy)carbonyl]amino}-3,3-dimethylbutanoic acid); 3,3-Dimethyl-4-[(tert-butoxycarbonyl)amino]butyric acid; N-Boc-3,3-dimethyl-4-aminobutyric acid; tert-Butyl (4-carboxy-2,2-dimethylbutyl)carbamate
EINECS	Contact for details

Quality Control

Our production of Butanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3,3-Dimethyl- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.