Description

3-Ethoxy-5-Aminopyridine-4-Boronic Acid is a high-value boronic acid derivative that serves as a versatile building block in modern synthetic chemistry. Its molecular structure, featuring both an amino and a boronic acid functional group on a pyridine core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a crucial boron-containing coupling partner for forming carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science & OLED Development: Serves as a building block for creating advanced organic electronic materials, such as electron-transport layers and emissive materials.
• Chemical Biology & Probe Synthesis: Utilized in the design and synthesis of molecular probes and sensors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific custom synthesis projects requiring specialized boronic acid derivatives.

Basic Information

Product Name	3-Ethoxy-5-Aminopyridine-4-Boronic Acid
CAS No.	1310405-08-3
Molecular Formula	C7H11BN2O3
Molecular Weight	181.99 g/mol
Synonyms	5-Amino-3-ethoxypyridine-4-boronic acid; (5-Amino-3-ethoxypyridin-4-yl)boronic acid; 4-Borono-5-amino-3-ethoxypyridine; 3-Ethoxy-5-aminopyridine-4-boronic acid pinacol ester (common protected form); 1310405-08-3; 5-Amino-3-ethoxy-4-pyridineboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Ethoxy-5-Aminopyridine-4-Boronic Acid is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.