Description

6-Butoxypyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester, crucial for synthesizing biphenyl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific pyridine-based architectures.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Organic Electronic Materials: A building block for constructing conjugated molecules and polymers for use in OLEDs, OFETs, and other electronic applications.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	6-Butoxypyridine-3-Boronic Acid Pinacol Ester
CAS No.	1310404-88-6
Molecular Formula	C₁₅H₂₄BNO₃
Molecular Weight	277.17 g/mol
Synonyms	2-(6-Butoxypyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Butoxy-3-pyridineboronic acid pinacol ester; 3-Boronic acid, 6-butoxypyridine-, pinacol ester; 6-n-Butoxypyridine-3-boronic acid pinacol ester; (6-Butoxypyridin-3-yl)boronic acid pinacol ester; Pinacol 6-butoxypyridine-3-boronate
EINECS	Contact for details

Quality Control

Every batch of 6-Butoxypyridine-3-Boronic Acid Pinacol Ester is produced and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, typically determined by advanced analytical techniques including NMR, HPLC, and GC. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and high-value research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.