Description

6-Chloropyrazin-2-Yl-2-Boronic Acid is a high-value boronic acid derivative and a key synthetic building block in modern organic chemistry. Its primary importance lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic systems. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science: Serves as a precursor for creating functionalized polymers and organic electronic materials.
• Chemical Research & Development: A fundamental reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Chloropyrazin-2-Yl-2-Boronic Acid
CAS No.	1310404-64-8
Molecular Formula	C4H3BClN2O2
Molecular Weight	172.34 g/mol
Synonyms	(6-Chloropyrazin-2-yl)boronic acid; 2-Borono-6-chloropyrazine; 6-Chloro-2-pyrazineboronic acid; 6-Chloropyrazine-2-boronic acid; 6-Chloro-2-pyrazinylboronic acid; B-(6-Chloro-2-pyrazinyl)boronic acid; 1310404-64-8
EINECS	Contact for details

Quality Control

Our 6-Chloropyrazin-2-Yl-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.