Description

4-(2-Hydroxypropan-2-Yl)Pyridine-2-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, serving as a key intermediate in cross-coupling reactions like the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its boronic acid functionality for carbon-carbon bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Academic & Industrial R&D: A versatile reagent for method development and exploratory synthesis in both academic laboratories and industrial R&D centers.

Basic Information

Item	Details
Product Name	4-(2-Hydroxypropan-2-Yl)Pyridine-2-Boronic Acid
CAS No.	1310385-00-2
Molecular Formula	C8H12BNO3
Molecular Weight	181.00 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(2-hydroxypropan-2-yl)pyridine; 4-(2-Hydroxy-2-propyl)pyridine-2-boronic acid; 4-(1-Hydroxy-1-methylethyl)-2-pyridineboronic acid; 2-Borono-4-(2-hydroxy-2-propyl)pyridine; 4-tert-Butylpyridine-2-boronic acid (common name derivative); 4-(2-Hydroxypropan-2-yl)pyridine-2-boronic acid pinacol ester (protected form); 4-(2-Hydroxy-2-propyl)-2-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Our 4-(2-Hydroxypropan-2-Yl)Pyridine-2-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.