Description

4-[(tert-Butoxycarbonyl)Amino]-6-Methylpyridine-3-Boronic Acid is a high-value, multi-functional chemical building block essential for modern synthetic chemistry. This compound matters because it combines a protected amine group with a versatile boronic acid functionality, enabling precise and efficient cross-coupling reactions. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its boronic acid group for creating diverse aromatic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or organic semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of chemical probes and affinity tags for studying protein interactions and enzyme activity.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for custom synthesis projects requiring specific, high-purity boronic acid derivatives.
• Academic Research: Utilized in university and institutional labs for methodological development in organoboron chemistry and catalysis studies.

Basic Information

Product Name	4-[(tert-Butoxycarbonyl)Amino]-6-Methylpyridine-3-Boronic Acid
CAS No.	1310384-83-8
Molecular Formula	C11H17BN2O4
Molecular Weight	252.08 g/mol
Synonyms	Boc-6-Methylpyridin-3-yl-4-amineboronic Acid; 3-Borono-6-methyl-4-[(tert-butoxycarbonyl)amino]pyridine; 4-(Boc-amino)-6-methylpyridine-3-boronic acid; 6-Methyl-4-((tert-butoxycarbonyl)amino)pyridine-3-boronic acid; tert-Butyl (3-borono-6-methylpyridin-4-yl)carbamate; 4-(N-Boc-amino)-6-methyl-3-pyridineboronic acid; (4-((tert-Butoxycarbonyl)amino)-6-methylpyridin-3-yl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-[(tert-Butoxycarbonyl)Amino]-6-Methylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) with full characterization data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.