Description

3-Methyl-5-Nitropyridine-2-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and a key building block in modern synthetic chemistry. Its core value lies in its role as a protected boronic acid derivative, enabling critical carbon-carbon bond-forming reactions like the Suzuki-Miyaura cross-coupling. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of complex drug candidates, particularly in medicinal chemistry programs targeting new small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, protected boronic acid reagent for forming biaryl and other C-C bonds under mild conditions, a cornerstone of modern organic synthesis.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides that require specific nitropyridine motifs for biological activity.
• Material Science & OLED Development: Acts as a precursor for creating organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Synthesis: Employed in the creation of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Methyl-5-Nitropyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310384-01-0
Molecular Formula	C12H17BN2O4
Molecular Weight	264.09 g/mol
Synonyms	(3-Methyl-5-nitropyridin-2-yl)boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-5-nitropyridine; 3-Methyl-5-nitro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-Nitro-3-methylpyridine-2-boronic acid pinacol ester; Pinacol (3-Methyl-5-nitropyridin-2-yl)boronate; Boronic acid, B-(3-methyl-5-nitro-2-pyridinyl)-, 1,1-dimethylethyl ester (9CI); CAS 1310384-01-0
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-Nitropyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.