Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-2-Carbaldehyde is a high-value, multi-functional boronic ester building block essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, to construct complex heterocyclic architectures. This compound is critically needed by researchers and process chemists in pharmaceutical development, agrochemical synthesis, and materials science for creating advanced molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyridine and bipyridine scaffolds for kinase inhibitors and other therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific heterocyclic motifs for bioactivity.
• Ligand and Catalyst Development: Serves as a building block for creating sophisticated bidentate and polydentate ligands used in catalysis and coordination chemistry.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics, where conjugated pyridine-boronate structures are valuable.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for studying biological processes and target engagement.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and exploring new chemical space.

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-2-Carbaldehyde
CAS No.	1310383-53-9
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	2-Formyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinaldehyde; 2-Pyridinecarboxaldehyde, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol 2-Formylpyridine-6-boronate; 6-(Pinacolatoboryl)picolinaldehyde; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-6-carbaldehyde
EINECS	Contact for details

Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.