Description

6-(3-Hydroxypyrrolidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a sophisticated boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those containing heterocyclic scaffolds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile coupling partner for the introduction of the pyridine-pyrrolidinyl moiety into target molecules.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Acts as a building block for creating novel ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the construction of molecular probes for studying biological pathways and target engagement.
• Material Science: Potential intermediate for the synthesis of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-(3-Hydroxypyrrolidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1310383-03-9
Molecular Formula	C15H23BN2O3
Molecular Weight	290.17 g/mol
Synonyms	6-(3-Hydroxypyrrolidin-1-yl)pyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(3-hydroxypyrrolidin-1-yl)pyridine; 6-(3-Hydroxy-1-pyrrolidinyl)-2-pyridineboronic acid pinacol ester; 1310383-03-9; 6-(3-Hydroxypyrrolidin-1-yl)-2-pyridinylboronic acid pinacol ester; Pinacol [6-(3-hydroxypyrrolidin-1-yl)pyridin-2-yl]boronate
EINECS	Contact for details

Quality Control

Our 6-(3-Hydroxypyrrolidin-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and cGMP-compliant manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.