Description

2-Ethoxy-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry. This compound matters because it serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing new active ingredients and functional molecules, where its boronic ester functionality provides exceptional versatility and stability for Suzuki-Miyaura couplings.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Suzuki-Miyaura Cross-Coupling: A premier reagent for forming carbon-carbon bonds between aromatic rings, a fundamental transformation in medicinal and process chemistry.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and labeled compounds for diagnostic and research applications.
• Catalyst & Ligand Preparation: Serves as a precursor for sophisticated ligands used in homogeneous catalysis.

Basic Information

Product Name	2-Ethoxy-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1309982-67-9
Molecular Formula	C15H24BNO3
Molecular Weight	277.17 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethoxy-4-methylpyridine; 2-Ethoxy-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Methyl-2-ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Ethoxy-4-methylpyridine-5-boronic acid pinacol ester; Pyridine, 2-ethoxy-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1309982-67-9
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-4-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.