Description

5-(tert-Butoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic ester building block essential for modern synthetic chemistry. This compound is a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily used by medicinal chemists and process R&D scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing pyridine-containing scaffolds via cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry: Used in the research and development of small molecule libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Employed in the creation of advanced pyridine-based herbicides, fungicides, and insecticides.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science: Utilized in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology: Acts as a probe or linker in bioconjugation chemistry and the development of chemical tools for biological studies.

Basic Information

Product Name	5-(tert-Butoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester
CAS No.	1309982-38-4
Molecular Formula	C₁₇H₂₆BNO₄
Molecular Weight	319.21 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-[(2-methylpropan-2-yl)oxycarbonyl]pyridine; 5-(Boc)-3-Pyridineboronic Acid Pinacol Ester; tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-5-carboxylate; 5-(tert-Butoxycarbonyl)-3-pyridylboronic Acid Pinacol Ester; Boc-3-Pyridyl-Bpin; 1309982-38-4; 5-Boc-3-pyridylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 5-(tert-Butoxycarbonyl)Pyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.