Description

6-(4-Methylpiperazin-1-Yl)Pyridine-2-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its primary commercial value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a building block for creating novel organic electronic materials, ligands for catalysts, and advanced polymers.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a boronic acid coupling partner with aryl/heteroaryl halides to form carbon-carbon bonds under palladium catalysis.
• Chemical Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.
• Ligand Synthesis: Used to prepare sophisticated chelating ligands for transition metal catalysts in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	6-(4-Methylpiperazin-1-Yl)Pyridine-2-Boronic Acid
CAS No.	1309981-34-7
Molecular Formula	C10H16BN3O2
Molecular Weight	221.07 g/mol
Synonyms	6-(4-Methyl-1-piperazinyl)-2-pyridineboronic acid; 2-Borono-6-(4-methylpiperazin-1-yl)pyridine; 6-(4-Methylpiperazin-1-yl)pyridine-2-boronic acid pinacol ester (protected form); 2-(4-Methylpiperazin-1-yl)-6-pyridineboronic acid; [6-(4-Methylpiperazin-1-yl)pyridin-2-yl]boronic acid; 1309981-34-7; 6-(N-Methylpiperazino)pyridine-2-boronic acid
EINECS	Contact for details

Quality Control

Our 6-(4-Methylpiperazin-1-Yl)Pyridine-2-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.