Description

1-[1,3-Dimethyl-4-(Trifluoromethyl)-1H-Pyrazolo-[3,4-B]Pyridin-6-Yl]Piperidine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure, designed for precision synthesis. This compound is valued for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for new chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Used in the development and scale-up processes for new active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Potential use in the development of biochemical probes for target validation and assay development in life sciences.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	1-[1,3-Dimethyl-4-(Trifluoromethyl)-1H-Pyrazolo-[3,4-B]Pyridin-6-Yl]Piperidine-4-Carboxylic Acid
CAS No.	1308649-27-5
Molecular Formula	C16H17F3N4O2
Molecular Weight	354.33 g/mol
Synonyms	1-(1,3-Dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl)piperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-[1,3-dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-; PF-06409577 carboxylic acid derivative; 1308649-27-5; 1-(1,3-Dimethyl-4-trifluoromethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)piperidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-[1,3-Dimethyl-4-(Trifluoromethyl)-1H-Pyrazolo-[3,4-B]Pyridin-6-Yl]Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and quality assurance for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.