Description

4-Bromo-1-Ethyl-1H-Pyrrole-2-Carbonitrile is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique pyrrole core enables the construction of novel active ingredients. It is primarily needed by R&D chemists and process development scientists working on drug discovery, material science, and the synthesis of specialty fine chemicals. Its reactivity profile makes it a valuable precursor for cross-coupling reactions and further functionalization.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or precursor for conducting polymers, organic semiconductors, and advanced organic electronic materials.
• Organic Synthesis & Catalysis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex, functionalized pyrrole derivatives for further research.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes, enzyme inhibitors, and tool compounds for biological target validation.
• Dye & Pigment Industry: Functions as a precursor for synthesizing specialized heterocyclic dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	4-Bromo-1-Ethyl-1H-Pyrrole-2-Carbonitrile
CAS No.	1308384-54-4
Molecular Formula	C7H7BrN2
Molecular Weight	199.05 g/mol
Synonyms	1-Ethyl-4-bromo-1H-pyrrole-2-carbonitrile; 4-Bromo-1-ethyl-2-cyanopyrrole; 1H-Pyrrole-2-carbonitrile, 4-bromo-1-ethyl-; 4-Bromo-1-ethylpyrrole-2-carbonitrile; 2-Cyano-4-bromo-1-ethylpyrrole; 1-Ethyl-4-bromopyrrole-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Ethyl-1H-Pyrrole-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.