Description

Pyridine, 2-[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-Methyl- is a high-purity, chiral oxazoline-substituted pyridine derivative, serving as a sophisticated building block in advanced organic synthesis. Its value lies in its role as a key chiral ligand or intermediate for catalyzing asymmetric transformations and constructing complex pharmaceutical scaffolds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty fine chemical industries who require precise stereochemical control.

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation, cyclopropanation, and cross-coupling reactions.
• As a critical pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs) with specific stereochemistry.
• In the research and development of agrochemicals, such as herbicides and fungicides, requiring enantioselective activity.
• As a building block for advanced materials and specialty polymers where chirality influences material properties.
• For use in academic and industrial R&D exploring new methodologies in organometallic chemistry and catalysis.
• In the synthesis of diagnostic reagents and other fine chemicals where high purity and defined stereochemistry are paramount.

Basic Information

Product Name	Pyridine, 2-[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-Methyl-
CAS No.	1308311-03-6
Molecular Formula	C15H14N2O
Molecular Weight	238.29 g/mol
Synonyms	(S)-2-(4,5-Dihydro-4-phenyl-2-oxazolyl)-6-methylpyridine; (4S)-4,5-Dihydro-4-phenyl-2-(6-methyl-2-pyridinyl)-2-oxazoline; 6-Methyl-2-[(4S)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]pyridine; (S)-6-Methyl-2-(4-phenyl-4,5-dihydrooxazol-2-yl)pyridine; Chiral Oxazoline-Pyridine Ligand; (S)-PHOX-Type Ligand Derivative; 2-[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-Picoline
EINECS	Contact for details

Quality Control

Our Pyridine, 2-[(4S)-4,5-Dihydro-4-Phenyl-2-Oxazolyl]-6-Methyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic and synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.